Special Issue Information

Bio-thermophysics, as an interdisciplinary frontier, explores the intricate interactions between thermal energy and biological systems. This field is rapidly evolving, driven by innovations in thermal science that provide profound insights into biological processes and enable groundbreaking biomedical technologies. From the thermodynamic principles governing cellular functions to the development of advanced thermal therapies for precision medicine, bio-thermophysics is reshaping our understanding and manipulation of life sciences.

We are pleased to announce this Special Issue on "Recent Advances in Bio-thermophysics: Innovations and Development at the Intersection of Biology and Thermal Science" in Thermo-X. This Issue aims to compile high-impact research and review articles that highlight the latest discoveries, methodologies, and applications at the confluence of biology and thermal science. We seek to foster discussions that bridge fundamental theoretical models with practical engineering solutions for healthcare and biology.

We invite the submission of Original Research Articles, Reviews, and Perspectives covering topics including, but not limited to:

• Thermodynamic Modeling of Cellular Processes: Theoretical and computational models of heat and mass transfer in cellular environments; entropy production and energy conversion in metabolic pathways; non-equilibrium thermodynamics in living systems.
• Thermal Management in Biomedical Devices: Innovation in heat dissipation for implantable electronics; thermal design of wearable health monitors; cryopreservation technologies and thermal management of bio-specimens.
• Novel Thermal Therapies for Disease Treatment: Advancements in thermal ablation (e.g., radiofrequency, microwave, laser); magnetic hyperthermia for cancer therapy; cryosurgery; photothermal therapy with novel agents; and the bio-thermophysical mechanisms underlying treatment efficacy.
• Nanoscale Heat Transfer in Biological Systems: Heat transport phenomena at the nanobio-interface; thermal characterization of biomolecules (e.g., proteins, DNA); applications of nanomaterials as thermal probes or actuators in biological environments.
• Multiphysics and multiscale modeling: from nanoscale heat generation to tissue-level respons; heat and mass transport across spatial and temporal scales.
• Interdisciplinary Applications: Combined thermal and optical/acoustic/mechanical techniques
(e.g., opto-thermo-acoustic-mechanical coupling) for biomedical imaging, sensing, and manipulation.

Submissions that present experimental, theoretical, or computational approaches with a clear focus on thermal mechanisms in biological contexts are particularly welcome.

We encourage researchers, engineers, and clinicians worldwide to contribute to this exciting Special Issue. All manuscripts will undergo a rigorous peer-review process to ensure scientific quality and relevance. The submission deadline is April 30, 2026.

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