Carbonization of Seaweed Polysaccharides for Biomedical Applications
Time
3:00 PM, March 6, 2026 (Beijing)Contact Us
Email: bmehjournal@sciexplor.comSpeaker
Prof. Chih-Ching Huang
Department of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan.
Prof. Chih-Ching Huang is a Professor in the Department of Bioscience and Biotechnology at National Taiwan Ocean University, with a joint appointment at the School of Pharmacy, Kaohsiung Medical University. His research focuses on antimicrobial materials, biomimetic self-assembled materials, drug delivery, nanozymes, and nano-immunotherapy. Over the past five years, he has published numerous high-impact papers in journals such as Biomaterials, ACS Nano, and Small. Prof. Huang serves on the Editorial Boards of Applied Sciences, Journal of Analytical Methods in Chemistry, Journal of the Chinese Chemical Society, and Physchem. He is also an Associate Editor for Frontiers in Drug Delivery and Cardiovascular Drug Delivery. He also reviews for leading journals including ACS Nano, Biomaterials, Anal. Chem., and Biosens. Bioelectron. He has received numerous prestigious awards, including the Ta-You Wu Memorial Award and the Outstanding Research Award from Taiwan’s National Science and Technology Council, and is widely recognized for his contributions to nanomaterials-enabled biomedical applications and disease diagnosis.
Introduction
This presentation will introduce recent advances in the development of functional carbonized nanomaterials derived from renewable seaweed polysaccharides, and will present a solvent-free, thermally driven carbonization strategy integrated with dehydration and hyperpolymerization chemistry. Through this approach, diverse marine polysaccharides are transformed into water-dispersible carbonized nanogels featuring programmable edge and surface functionalities. By rationally tuning precursor selection, chemical modification, and carbonization conditions, these materials can be optimized for multivalent biomolecular interactions and exhibit broad bioactivities, including antioxidative, anti-inflammatory, antimicrobial, anticoagulant/antithrombotic, antiviral, and antitumor/anti-metastatic effects. Representative case studies demonstrate their potential in oral antithrombotic therapy, influenza virus inhibition, targeted suppression of triple-negative breast cancer metastasis, and intraocular anti-angiogenic treatment. In addition, this presentation will explore how “edge-state–programmed” surfaces enable enzyme-specific binding and release for antibody-free hot-start PCR–based molecular diagnostics, and will discuss key translational considerations such as safety, reproducibility, and scalable manufacturing.
